ČSN EN ISO 19238 (404304)

Radiological protection - Performance criteria for service laboratories performing biological dosimetry by cytogenetics - Dicentric assay

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STANDARD published on 1.2.2024


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The information about the standard:

Designation standards: ČSN EN ISO 19238
Classification mark: 404304
Catalog number: 518364
Publication date standards: 1.2.2024
SKU: NS-1165055
The number of pages: 56
Approximate weight : 168 g (0.37 lbs)
Country: Czech technical standard
Category: Technical standards ČSN

The category - similar standards:

Radiation protectionRadiation measurements

Annotation of standard text ČSN EN ISO 19238 (404304):

This document provides criteria for quality assurance and quality control, evaluation of the performance and the accreditation of biological dosimetry by cytogenetic service laboratories using the dicentric assay performed with manual scoring.

This document is applicable to

a) the confidentiality of personal information, for the requestor and the service laboratory,

b) the laboratory safety requirements,

c) the calibration sources and calibration dose ranges useful for establishing the reference dose-response curves that contribute to the dose estimation from unstable chromosome aberration frequency and the detection limit,

d) the scoring procedure for unstable chromosome aberrations used for biological dosimetry,

e) the criteria for converting a measured aberration frequency into an estimate of absorbed dose,

f) the reporting of results,

g) the quality assurance and quality control, and

h) informative annexes containing sample instructions for requestor, sample questionnaire, sample report, fitting of the low dose-response curve by the method of maximum likelihood and calculating the error of the dose estimate, odds ratio method for cases of suspected exposure to a low dose, a method for determining the decision threshold and detection limit and sample data sheet for recording aberrations

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